“Whatever we checked, taurine-supplemented mice were healthier and appeared younger than the control mice,” Yadav said, noting they had denser bones, stronger muscles, better memory and younger looking immune systems. The discovery prompted the team to test the impact of extra taurine on middle-aged mice. By the age of 60, taurine levels in a typical person slumped to one-third of that seen in five-year-olds, they found. Yadav’s team homed in on taurine as a potential driver of the ageing process in 2012 when an analysis of blood compounds found that levels of the amino acid dropped dramatically with age in mice, monkeys and humans. “It will probably be very difficult to look at whether they live longer, but at least we can check if they live healthier for longer, and that of course is the goal for medicine.” Prof Henning Wackerhage, a molecular exercise physiologist on the team at the Technical University of Munich, said a trial would compare how humans fared after taking daily taurine or placebo supplements. “At the end of the day, these findings should be relevant to humans.” “Taurine abundance declines with age and reversal of this decline makes animals live longer and healthier lives,” said Dr Vijay Yadav, who led the research at Columbia University in New York.
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